Large doses of vitamin C may interfere with the absorption and metabolism of vitamin B12. so you never give it with the vit C
Submitted 403 days ago...
Large doses of vitamin C may interfere with the absorption and metabolism of vitamin B12. so you never give it with the vit C
So if Vit C interferes with the metabolism of vit B12, could that cause a build up of mercury in the body? What do you think the physician was talking about in regards to the mercury? And would Vit C affect the absorbtion of Vit B12 if B12 was given IM instead of with the IV VitC, if so, how long should you wait before giving Vit B12 (where the vit c wouldn't affect the absorption)
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Answer 3 / 3 - Submitted 403 days ago...
NO he was talking about the body having mercury build up already like from eating fish and some people have more so called more metal in their systems then others and The transport of vitamin B12 to the brain can be disturbed or interrupted by heavy metals such as mercury, which affects the blood-brain barrier by causing leakage and hampering the active transport of nutrients. In regard to heavy metal toxicity, in many cases it can be assumed that multiple deficiencies, not always easily separable, can be found."
"Vitamin B12 deficiencies have been mainly related to blood deficiency diseases such as pernicious anaemia. Mercury seems to change valency and binding site in the body, and this causes increased free radical formation. It is possible that the mercury change in valency in pro-oxidative direction, oxidises the cobalt atom in the B12. Due to its molecular size, vitamin B12 normally has difficulties in crossing the blood-brain barrier, and it is possible that denaturation makes this even more difficult." and vit C will destroy this because of its radical path through the system. this works against each other in the right words!
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So do you feel adding Vit B12 to an IV of Vit C is ok to do, as long as you don't have mercury poisioning?
Yes i do think this and it should not be a problem !
This article I found, I believe is some what, what you were mentioning eairler.
article from Dr. Hal Huggins, DDS, MS.....( guess it is just in regards to mercury poisoning?) States... Do not, in any way, accept B12 in your IV. Vit B12 in an IV has been shown to methylate mercury, which means it turns the mercury into an even more poisonous, dangerous compound.
T his is what i think this refers to and this is interesting isn't it! The mercuric ion (Hg2+) is methylated in the sediment of aquatic systems to give methylmercury (CH3Hg+), which is bioaccumulated in fish and has high toxicity for humans. Methylpobalamin, the methyl derivative of vitamin B12 and a coenzyme in enzymatic methyl transfer, Is able to methylate mercury(II). In the chemical reaction, the mercuric Ion acts as an electrophile towards methylcobalamin in aqueous solution, giving aquocobalamin and methylmercury. It has been shown that sulphate-reducing bacteria, Desulphovibrio desulfuricans, methylate mercury(II) in aquatic sediments and that they use methylcobalamin to methylate mercuric ion. The methylation of mercury may be promoted by a synergistic interaction between sulphate-reducing bacteria and methanogens.
Yes, it is interesting, and I believe you explained it very well, I understand it as well as my nursing education allows, just wish I had a degree in biochemistry.
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